Pain Clinical Trials in New York, NY

This study aims to assess the differences in overall pain severity, pain management, and satisfaction during recovery period between two groups of children who either receive or do not receive additional education related to expectation and management of postoperative pain. Read Less

The purpose of this study is to evaluate the efficacy, safety, and tolerability of Suzetrigine (SUZ) in participants with pain associated with diabetic peripheral neuropathy (DPN). Read Less

The overall objective of this multi-center registry is to identify specific phenotypes of INOCA with both an anatomic evaluation (coronary angiography and intravascular imaging) and physiologic assessment with the Abbott Coroventis Coroflow Cardiovascular System, and to determine long-term outcomes. Read Less

There is currently limited literature on a categorized physical therapy protocol for management of hip pain. Only a handful of studies have looked at the treatment of osteoarthritis of the hip with a standardized physical therapy treatment, primarily looking at manual therapy versus exercise therapy protocols. However, there are no studies observing the effect of a standardized physical therapy program on patients presenting with non-arthritic hip and groin pain. Based on the gap in the literature, this study will aim to assess the effect of matrix-based standard of care therapy in patients presenting with non-arthritic hip and groin pain. Read Less

To compile characteristics of real-world clinical outcomes for Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice, when used according to the applicable Directions for Use - and - To evaluate the economic value and technical performance of Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice Read Less

This study is a double-blind, randomized, placebo-controlled trial to evaluate the use of high frequency TENS for pain control during IUD insertion. Transcutaneous electrical nerve stimulation (TENS) is a relatively low-cost, low-risk, non-pharmacologic intervention for pain management. Previous studies have found that TENS reduces pain associated with other outpatient gynecological procedures. Participants will be randomized in a 1:1 ratio to either active treatment or placebo (placebo TENS) and record pain scores using a 100 mm visual analog scale (VAS) at the time of IUD insertion. The same device will be used for both active and placebo treatment. Read Less

Negative pressure wound therapy (NPWT) has become a common primary or adjunctive treatment approach for more than 100 indications, including chronic complex wounds that are potentially non-healing, and acute open wounds that are infected or subject to swelling, severe burns, and post-operative surgical care. Despite demonstrated benefits of NPWT, the technology faces challenges regarding the adhesive sealant component of the system as the strong adhesive required to establish and maintain an airtight seal for successful implementation of NPWT substantially increases the chances for additional or new mechanical skin injuries and severe discomfort and pain to the patient during removal. Addressing this, Global Biomedical Technologies ("GBT") proposes to develop a specialized adhesive NPWT drape with an innovative "switchable adhesive" technology for improved removal and replacement. This GBT technology is expected to have value in both single-use and serial-use applications by creating a strong airtight seal while allowing for easy removal without injuring fragile peri-wound skin. This project will compare the functionality and acceptability of Comfort Release® NPWT drapes against the state-of-the art (V.A.C. drape by KCI Technologies, Inc.) in both single-use and serial-use NPWT applications. The project is non-blinded. Specific Aims are as follows: Aim 1) Compare performance of Comfort Release® drapes with V.A.C. drapes in single-use NPWT applications in a randomized controlled trial. Post-surgical patients (n=200) will be enrolled at Columbia University Medical Center or at Weill Cornell Medical Center. Milestones: To demonstrate that compared to current market leader (VAC NPWT drapes), patients with the Comfort Release® drapes have statistically significant (α=0.05): ): 1) decrease in medical adhesive-related skin irritation and injuries, as measured by the Medical Adhesive-Related Skin Injury (MARSI) scoring system, 2) reduction of pain, as measured by the Indiana Polyclinic Combined Pain Scale, 3) decreased use of medications for pain and stress related to dressing removal, 4) demonstrate equivalent or improved effectiveness in maintaining seal (leak incidence rate), and 5) establish clinician acceptability of the Comfort Release® drape. 2) Compare the performance of Comfort Release® drapes with V.A.C. drapes in serial-use NPWT applications in a randomized controlled trial. Chronic wound patients (n=100) will be enrolled at Weil Cornell Medical Center where they will undergo 3 NPWT drape changes per week. Milestones: To demonstrate that compared to VAC NPWT drapes, patients with Comfort Release® drapes have statistically significant (α=0.05): 1. decrease in medical adhesive-related skin irritation and injuries, as measured by the Medical Adhesive-Related Skin Injury (MARSI) scoring system, 2. reduction of pain, as measured by the Indiana Polyclinic Combined Pain Scale, 3. improved compliance to the full duration of treatment as prescribed by clinician, 4. decreased use of medications for pain and stress related to dressing removal, 5. demonstrate equivalent or better effectiveness in maintaining seal compared to control (leak incidence rate), 6. establish clinician acceptability (questionnaire score \>4), 7. demonstrate the ability of Comfort Release® drape to reduce nursing time by at least 20% and, 8. demonstrate significant time added economic value through economic analysis. Thus, at each drape change and on final drape removal, qualitative data will be collected from clinicians participating in each aim to assess clinician acceptability of the Comfort Release® drape. Read Less

This is a two phase study. In phase 1, a focus group (N=5) will be conducted to adapt MBCT-T for use in the study population. In phase 2, a single-arm trial will be conducted examining four, weekly sessions of preoperative MBCT-T in subjects with high pain catastrophizing scheduled for spine surgery (N=20). Subjects will then be followed for two weeks postoperatively. Read Less

This study seeks to evaluate the impact of intra-operative topical epidural steroid usage in patients undergoing 1-2 level lumbar laminectomy. The study will examine post-operative opioid usage, length of stay, return to work, and patient reported outcomes following these procedures. Read Less

The goal of this interventional study is to explore the use of InfraRed (FLIR) imaging in determining pain intensity and severity in newly diagnosed complex regional pain syndrome patients. The main questions it aims to answer are: Question 1: Can Infrared (FLIR) imaging be used to determine the severity of CRPS in newly diagnosed patients? Question 2: Is there any correlation with the quantification of 'the Δ thermal index value' measured by FLIR imaging with pain intensity (NRS) in newly diagnosed patients? Question 3: Is there any correlation between the quantification of 'the Δheat index value' measured by FLIR imaging between the two extremities with the severity (the severity score for CRPS) in newly diagnosed patients? Participants will have a picture of their foot taken using the forward looking infrared (FLIR) camera and answer questionnaires regarding their pain and complex regional pain syndrome (CRPS). Read Less

The goal of this observational study is to learn if surgical weight loss can improve chronic widespread pain in people living with higher BMI who self-identify as Hispanic/Latino ethnicity or non-Hispanic Black based on the United States census racial categories. The main questions the study aims to answer are: 1. Do pain at rest (primary outcome) and movement-evoked pain (secondary outcome) improve after bariatric surgery? 2. Do pain processing and joint function change after bariatric surgery? 3. Are pain processing and joint function associated with clinically significant pain change after surgical weight loss? Researchers will compare pain and function before and 6 months after bariatric surgery in a single cohort. Read Less

The researchers are doing this study to find out whether stereotactic radiosurgery (SRS) is a safe, practical (feasible), and effective treatment for people with chronic TAWP. The researchers will test different doses of SRS to find the highest dose that causes few or mild side effects. Read Less